Identification of the ceRNA axis of circ_0000006/miR-483-5p/KDM2B in the progression of aortic aneurysm to aorta dissection

Abstract excerpt

<title>Abstract</title> <p>Background Aortic aneurysm (AA) and aortic dissection (AD) are serious cardiovascular disorders with a high risk of mortality. The molecular mechanisms underlying the progression from AA to AD are not well understood. This study aimed to identify the key circular RNA (circRNA)-microRNA (miRNA)-messenger RNA (mRNA) regulatory axis involved in this disease progression. Methods CircRNA m...

Topics

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• Aortic Aneurysm
• Aortic Dissection
• Cell Movement
• Gene Regulatory Networks
• MicroRNAs
• Muscle, Smooth, Vascular
• Myocytes, Smooth Muscle
• RNA, Circular

Identifiers and source

Literature Corpus work

343e8cf2-7304-5b1b-8525-b79ebd50708f

DOI

10.21203/rs.3.rs-4544309/v1