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Article

E2F1 rs3213150 polymorphism influences cytarabine sensitivity and prognosis in patients with acute myeloid leukemia.

Annals of hematology - 1 Dec 2023

Liu Yanfeng, Chen Peng, Chen Ge, Chen Xiaoping

Abstract excerpt

Cytarabine (Ara-C) plays an irreplaceable role in the treatment of acute myeloid leukemia (AML). However, there are significant differences in efficacy among patients. Our previous studies found that E2F1 rs3213150 polymorphism was associated with remission rate of Ara-C chemotherapy, but the specific mechanism is not clear. This study aimed to further confirm the correlation between E2F1 rs3213150 polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37665348
DOI: 10.1007/s00277-023-05431-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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