Article
SMAD4 and KCNQ3 alterations are associated with lymph node metastases in oesophageal adenocarcinoma.
Biochimica et biophysica acta. Molecular basis of disease - 1 Jan 2024
Foley Kieran, Shorthouse David, Rahrmann Eric, Zhuang Lizhe, Devonshire Ginny, Gilbertson Richard J, Fitzgerald Rebecca C, Hall Benjamin A
Abstract excerpt
Metastasis in oesophageal adenocarcinoma (OAC) is an important predictor of survival. Radiological staging is used to stage metastases in patients, and guide treatment selection, but is limited by the accuracy of the approach. Improvements in staging will lead to improved clinical decision making and patient outcomes. Sequencing studies on primary tumours and pre-cancerous tissue have revealed the mutational...
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