Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pan-cancer drivers of metastasis

2 Jan 2025

Abstract excerpt

Metastasis remains a leading cause of cancer-related mortality, irrespective of the primary tumour origin. However, the core gene regulatory program governing distinct stages of metastasis across cancers remains poorly understood. We investigate this through single-cell transcriptome analysis encompassing over two hundred patients with metastatic and non-metastatic tumours across six cancer types. Our analysis...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Cells and Metastasis
Share to Cancer Research and Treatments
Share to Histone Deacetylase Inhibitors Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39748426
DOI: 10.1186/s12943-024-02182-w

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pan-cancer drivers of metastasisPMID 39748426Read ↗

Deciphering molecular mechanisms of metastasis: novel insights into targets and therapeutics.Semantic proximity Read ↗

Decoding metastatic microenvironments through single-cell omics reveals new insights into niche dynamics and tumor evolutionSemantic proximity Read ↗

Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissuesSemantic proximity Read ↗

Tracing the origins of metastasis.Semantic proximity Read ↗

Unravelling the complexity of metastasis — molecular understanding and targeted therapiesSemantic proximity Read ↗

Cancer metastasis - tricks of the tradeSemantic proximity Read ↗

Charting the transcriptomic landscape of primary and metastatic cancers in relation to their origin and target normal tissuesSemantic proximity Read ↗

Origins of metastatic traits.Semantic proximity Read ↗

Defining the “Metastasome”: Perspectives from the genome and molecular landscape in colorectal cancer for metastasis evolution and clinical consequencesSemantic proximity Read ↗

Genomic control of metastasis.Semantic proximity Read ↗

Decoding the interplay between genetic and non-genetic drivers of metastasisSemantic proximity Read ↗

Insights into the metastatic cascade through research autopsiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.