Article
MLH1 rs1800734 Pathogenic Variant among Patients with Colorectal Cancer in the Lower Northeastern Region of Thailand.
Asian Pacific journal of cancer prevention : APJCP - 1 Aug 2023
Pongsavee Malinee, Wisuwan Kamol, Pongsavee Kritpipat
Abstract excerpt
BACKGROUND: The -93G > A (rs1800734) polymorphism within the core promoter region of MLH1 gene is associated with MLH1 CpG island hypermethylation. This polymorphism has recently been proposed as a low penetrance variant for colorectal cancer. Many published studies have evaluated the association between the MLH1 -93G > A polymorphism and colorectal cancer risk. However, the results remain conflicting rather than...
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