Article
Contribution of the MLH1 -93G>a promoter polymorphism in modulating susceptibility risk in Malaysian colorectal cancer patients.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Nizam Zahary Mohd, Abdul Aziz Ahmad Aizat, Kaur Gurjeet, Abu Hassan Muhammad Radzi, Mohd Sidek Ahmad Shanwani, Yeh Lee Yeong, Mazuwin Maya, Ankathil Ravindran
Abstract excerpt
BACKGROUND: Colorectal cancer (CRC) exists in a more common sporadic form and less common hereditary forms, associated with the Lynch syndrome, familial adenomatous polyposis (FAP) and other rare syndromes. Sporadic CRC is believed to arise as a result of close interaction between environmental factors, including dietary and lifestyle habits, and genetic predisposition factors. In contrast, hereditary forms such...
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