Article
Effect of statins on sepsis and inflammatory factors: A Mendelian randomization study
16 Jan 2024
Abstract excerpt
Abstract Background As inhibitors of 3‐hydroxy‐3‐methylglutaryl‐CoA reductase (HMGCR), statins can reduce the synthesis of low‐density lipoptrotein cholesterol (LDL‐C), and are clinically used as first‐line lipid‐lowering drugs to prevent cardiovascular diseases. However, the effect of statins on sepsis is controversial. Therefore, we intend to explore the effects of statins on sepsis and inflammatory factors...
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