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Article

Human blood metabolites and risk of sepsis: A Mendelian randomization investigation

2 Dec 2023

Abstract excerpt

BACKGROUND: Evidence supports the observational correlations between human blood metabolites and sepsis. However, whether these associations represent a causal relationship is unknown. In this study, we applied two-sample Mendelian randomization (MR) analyses to examine causality between genetically proxied 486 blood metabolites and sepsis risk. METHODS: We used summary data from genome-wide association studies...

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PMID: 38041600
DOI: 10.1111/eci.14145

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