Article
Association of Genetically Predicted Insomnia With Risk of Sepsis: A Mendelian Randomization Study.
JAMA psychiatry - 1 Oct 2023
Thorkildsen Marianne S, Gustad Lise T, Mohus Randi M, Burgess Stephen, Nilsen Tom I L, Damås Jan K, Rogne Tormod
Abstract excerpt
Importance: Insomnia has been associated with altered inflammatory response as well as increased risk of infections and sepsis in observational studies. However, these studies are prone to bias, such as residual confounding. To further understand the potential causal association between insomnia and sepsis risk, a 2-sample Mendelian randomization (MR) approach should be explored. Objective: To evaluate whether...
Topics
Join the communities discussing this publication.