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Article

Clinical Significance of bZIP In-Frame CEBPA-Mutated Normal Karyotype Acute Myeloid Leukemia.

Cancer research and treatment - 1 Jul 2023

Ahn Seo-Yeon, Kim TaeHyung, Kim Mihee, Song Ga-Young, Jung Sung-Hoon, Yang Deok-Hwan, Lee Je-Jung, Kim Mi Yeon, Jung Chul Won, Jang Jun-Ho, Kim Hee Je, Moon Joon Ho, Sohn Sang Kyun, Won Jong-Ho, Kim Sung-Hyun, Kim Hyeoung-Joon, Ahn Jae-Sook, Kim Dennis Dong Hwan

Abstract excerpt

PURPOSE: We evaluated the characteristics of CCAAT/enhancer-binding protein α (CEBPA) mutations and the significance of a basic leucine zipper in-frame mutation (bZIPin-f) of CEBPA in patients with acute myeloid leukemia with a normal karyotype. Materials and Methods: Based on updated knowledge of CEBPA mutations, we conducted next-generation sequencing analyses in a previously established real-world cohort....

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Identifiers

PMID: 36701843
DOI: 10.4143/crt.2022.1407
PMCID: PMC10372603

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