Article
CCAAT/enhancer-binding protein alpha basic leucine zipper in-frame insertion/deletion (CEBPA bZIP-InDel-inf) defines a favourable-prognosis subgroup in CEBPA-mutated acute myeloid leukaemia.
British journal of haematology - 1 Sept 2026
Yang Yankun, Tang Yuqian, Yang Kun, Zhang Ying, Tang Jirui, Liang Meiting, Gong Yuping
Abstract excerpt
This study investigated how cytosine-cytosine-adenine-adenine-thymine (CCAAT)/enhancer-binding protein alpha (CEBPA) mutation sites and types affect the prognosis of acute myeloid leukaemia (AML). It specifically analysed the clinical and genetic features of AML patients harbouring CEBPA basic leucine zipper in-frame insertion/deletion (CEBPA bZIP-InDel-inf) mutations and identified prognostic factors in this...
Read the complete abstract on PubMedTopics
- Humans
- Leukemia, Myeloid, Acute
- Prognosis
- CCAAT-Enhancer-Binding Proteins
- Female
- Middle Aged