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Article

Neurophysiological alterations in mice and humans carrying mutations in APP and PSEN1 genes.

Alzheimer's research & therapy - 22 Aug 2023

van Heusden Fran C, van Nifterick Anne M, Souza Bryan C, França Arthur S C, Nauta Ilse M, Stam Cornelis J, Scheltens Philip, Smit August B, Gouw Alida A, van Kesteren Ronald E

Abstract excerpt

BACKGROUND: Studies in animal models of Alzheimer's disease (AD) have provided valuable insights into the molecular and cellular processes underlying neuronal network dysfunction. Whether and how AD-related neurophysiological alterations translate between mice and humans remains however uncertain. METHODS: We characterized neurophysiological alterations in mice and humans carrying AD mutations in the APP and/or...

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Identifiers

PMID: 37608393
DOI: 10.1186/s13195-023-01287-6
PMCID: PMC10464047

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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