Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sleep and EEG Power Spectral Analysis in Three Transgenic Mouse Models of Alzheimer's Disease: APP/PS1, 3xTgAD, and Tg2576.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Kent Brianne A, Strittmatter Stephen M, Nygaard Haakon B

Abstract excerpt

BACKGROUND: Sleep disturbances have long been associated with Alzheimer's disease (AD), and there is a growing interest in how these disturbances might impact AD pathophysiology. Despite this growing interest, surprisingly little is known about how sleep architecture and the broader neuronal network are affected in widely used transgenic mouse models of AD. OBJECTIVE: We analyzed sleep and electroencephalography...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer Disease
Share to Amyloid beta-Peptides

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Amyloid beta-Protein Precursor

Share to Electroencephalography

Share to Mice, Inbred C57BL

Share to Mice, Transgenic

Share to Presenilin-1

Share to Sleep Wake Disorders

Source

Open in PubMed Open full text

Identifiers

PMID: 29991134
DOI: 10.3233/JAD-180260
PMCID: PMC6176720

Genes

APP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sleep and EEG Power Spectral Analysis in Three Transgenic Mouse Models of Alzheimer's Disease: APP/PS1, 3xTgAD, and Tg2576.PMID 29991134Read ↗

Progressive sleep disturbance in various transgenic mouse models of Alzheimer’s diseaseSemantic proximity Read ↗

Natural age-related sleep-wake alterations onset prematurely in the Tg2576 mouse model of Alzheimer’s diseaseSemantic proximity Read ↗

Sleep alterations in a mouse model of Spinocerebellar ataxia type 3Semantic proximity Read ↗

Neurophysiological alterations in mice and humans carrying mutations in APP and PSEN1 genes.Semantic proximity Read ↗

Long Wake/Short Sleep Bouts and Hyperactivity with Advanced Age in a Mouse Model of Early Onset Alzheimer’s DiseaseSemantic proximity Read ↗

Insights From TgF344-AD, a Double Transgenic Rat Model in Alzheimer’s Disease ResearchSemantic proximity Read ↗

Abnormal Cognition, Sleep, EEG and Brain Metabolism in a Novel Knock-In Alzheimer Mouse, PLB1Semantic proximity Read ↗

Early Loss of Deep Restorative Sleep and Auditory Stimulus Evoked 40-Hz activity of Hippocampal Parvalbumin Neurons in the APP/PS1 Mouse Model of Alzheimer’s DiseaseSemantic proximity Read ↗

Multitaper Time-frequency Peak-based Longitudinal Sleep Analysis in 5XFAD Mouse ModelSemantic proximity Read ↗

Circadian and sleep phenotypes in a mouse model of Alzheimer's disease characterized by intracellular accumulation of amyloid β oligomers.Semantic proximity Read ↗

Evaluating Circadian Dysfunction in Mouse Models of Alzheimer’s Disease: Where Do We Stand?Semantic proximity Read ↗

Chronic Sleep Disturbances Alters Sleep Structure and Tau Phosphorylation in AβPP/PS1 AD Mice and Their Wild-Type LittermatesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.