Article

Normal Aging in Mice is Associated with a Global Reduction in Cortical Spectral Power and Network-Specific Declines in Functional Connectivity

2021-06-10

Abstract excerpt

Normal aging is associated with a variety of neurologic changes including declines in cognition, memory, and motor activity. These declines correlate with neuronal changes in synaptic structure and function. Degradation of brain network activity and connectivity represents a likely mediator of age-related functional deterioration resulting from these neuronal changes. Human studies have demonstrated both general d...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: e99b9960-aed5-5b16-ab11-ccdfe081b0d2
DOI: 10.1101/2021.06.09.447772

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Normal Aging in Mice is Associated with a Global Reduction in Cortical Spectral Power and Network-Specific Declines in Functional ConnectivityDOI 10.1101/2021.06.09.447772Read

Neurophysiological alterations in mice and humans carrying mutations in APP and PSEN1 genes.Semantic proximity Read

Neuronal and physiological correlation to hemodynamic resting-state fluctuations in health and disease.Semantic proximity Read

Cerebral cortical functional hyperconnectivity in a mouse model of spinocerebellar ataxia type 8 (SCA8)Semantic proximity Read

Unique spatiotemporal fMRI dynamics in the awake mouse brainSemantic proximity Read

Functional connectivity favors aberrant visual network c-Fos expression accompanied by cortical synapse loss in a mouse model of Alzheimer’s diseaseSemantic proximity Read

Circuit-specific selective vulnerability in the DMN persists in the face of widespread amyloid burdenSemantic proximity Read

Alterations in Electroencephalography Signals in Female Fragile X Syndrome Mouse Model on a C57Bl/6J BackgroundSemantic proximity Read

Individual variability in functional connectivity architecture of the mouse brainSemantic proximity Read

Large-scale topology and the default mode network in the mouse connectomeSemantic proximity Read

Executive dysfunction is associated with altered hippocampal-prefrontal functional connectivity in male 3xTg Alzheimer’s model miceSemantic proximity Read

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome.Semantic proximity Read

Isolation of the murine Glut1 deficient thalamocortical circuit: wavelet characterization and reverse glucose dependence of low and gamma frequency oscillationsSemantic proximity Read