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Article

Alteration of cortical EEG in mice carrying mutated human APP transgene.

Brain research - 12 Jul 2002

Wang Jun, Ikonen Sami, Gurevicius Kestutis, van Groen Thomas, Tanila Heikki

Abstract excerpt

Transgenic mice expressing human APPswe and PS1-A264E mutations mimic certain neuropathological features of Alzheimer's disease (AD). These mice have elevated levels of the highly fibrillogenic amyloid beta1-42 peptide (Abeta42) and develop amyloid plaques around the age of 9 months. Our aim was...

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Source

Identifiers

PMID: 12101040
DOI: 10.1016/s0006-8993(02)02617-3

Genes

APP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12101040-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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