Article
Modelling cell adaptation using internal variables: Accounting for cell plasticity in continuum mathematical biology.
Computers in biology and medicine - 1 Sept 2023
Pérez-Aliacar Marina, Ayensa-Jiménez Jacobo, Doblaré Manuel
Abstract excerpt
Cellular adaptation is the ability of cells to change in response to different stimuli and environmental conditions. It occurs via phenotypic plasticity, that is, changes in gene expression derived from changes in the physiological environment. This phenomenon is important in many biological processes, in particular in cancer evolution and its treatment. Therefore, it is crucial to understand the mechanisms...
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