Article

Dynamic equilibrium of cellular plasticity: The origin of diseases

2023-04-04

Abstract excerpt

Since its inception, cellular plasticity has undergone many iterations. Today we define it as the ability of mature, terminally differentiated cells to change their identity, meaning lineage change of the cells by transdifferentiation, dedifferentiation and reprogramming. This process does not involve a single DNA sequence change or a mutation. We now know that the behavior of a cell is profoundly affected by the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: b254be68-aa48-5ad2-a32a-ed414c6937d2
DOI: 10.3389/fevo.2023.1077902

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dynamic equilibrium of cellular plasticity: The origin of diseasesDOI 10.3389/fevo.2023.1077902Read

[Cancer Cells as Dynamic System - Molecular and Phenotypic Changes During Tumor Formation, Progression and Dissemination].Semantic proximity Read

Epithelial–Mesenchymal Transition: From Molecular Mechanisms, Redox Regulation to Implications in Human Health and DiseaseSemantic proximity Read

Basic Biology of Hypoxic Responses Mediated by the Transcription Factor HIFs and Its Implication for MedicineSemantic proximity Read

Lineage Plasticity in Cancer Progression and TreatmentSemantic proximity Read

Intermittent hypoxia selects for genotypes and phenotypes that increase survival, invasion, and therapy resistance.Semantic proximity Read

Hypoxia signaling in human health and diseases: implications and prospects for therapeuticsSemantic proximity Read

[Plasticity of the cellular phenotype].Semantic proximity Read

Stress, genomic adaptation, and the evolutionary trade-offSemantic proximity Read

Hypoxia in Cancer and Fibrosis: Part of the Problem and Part of the SolutionSemantic proximity Read

Developmental plasticity of stem cells and diseases.Semantic proximity Read

Tumor cell plasticity: the challenge to catch a moving target.Semantic proximity Read

Transcriptomic profiling of healthy individual-derived LCLs revealed inter-individual variability towards-hypoxia-responsive pathwaysSemantic proximity Read