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Article

Designing of neoepitopes based vaccine against breast cancer using integrated immuno and bioinformatics approach.

Journal of biomolecular structure & dynamics - 1 Oct 2024

Shuaib Mohd, Singh Atul Kumar, Gupta Sanjay, Alasmari Abdullah F, Alqahtani Flaeh, Kumar Shashank

Abstract excerpt

Cancer is characterized by genetic instability due to accumulation of somatic mutations in the genes which generate neoepitopes (mutated epitopes) for targeting by Cytotoxic T lymphocytes (CTL). Breast cancer has a high transformation rate with unique composition of mutational burden and neoepitopes load that open a platform to designing a neoepitopes-based vaccine. Neoepitopes-based therapeutic cancer vaccines...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37584493
DOI: 10.1080/07391102.2023.2247081

Genes

ABCA13
ASPM
DNAH17
F5
MUC16
RYR2
TP53

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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