Article
A Platform for Designing Genome-Based Personalized Immunotherapy or Vaccine against Cancer.
PloS one - 1 Jan 2016
Gupta Sudheer, Chaudhary Kumardeep, Dhanda Sandeep Kumar, Kumar Rahul, Kumar Shailesh, Sehgal Manika, Nagpal Gandharva, Raghava Gajendra P S
Abstract excerpt
Due to advancement in sequencing technology, genomes of thousands of cancer tissues or cell-lines have been sequenced. Identification of cancer-specific epitopes or neoepitopes from cancer genomes is one of the major challenges in the field of immunotherapy or vaccine development. This paper describes a platform Cancertope, developed for designing genome-based immunotherapy or vaccine against a cancer cell....
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