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Immunogenic mutanome of breast cancer: Advances, challenges and future directions in neoantigen-based immunotherapy.

Advances in clinical and experimental medicine : official organ Wroclaw Medical University - 1 Feb 2026

Alkayyal Almohanad A, Saeedi Nizar H, Moawadh Mamdouh S

Abstract excerpt

Breast cancer (BC) remains a leading cause of cancer-related mortality worldwide, underscoring the need for novel, more effective therapies. Neoantigen-based immunotherapy - which harnesses tumor-specific somatic mutations to boost immune recognition - has emerged as a particularly promising strategy. Advances in next-generation sequencing and computational immunopeptidomics now allow systematic mapping of the...

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PMID: 40748773
DOI: 10.17219/acem/205014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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