Article

A Comprehensive Survey of Genomic Mutations in Breast Cancer Reveals Recurrent Neoantigens as Potential Therapeutic Targets

2020-02-12

Abstract excerpt

Neoantigens are newly formed antigens generated by cancer cells but absent in normal cells. With their high specificity and immunogenicity characteristic, neoantigens are considered as an ideal target for immunotherapy. This study was aimed to investigate the signature of neoantigens in breast cancer. Somatic mutations, including SNVs and indels, were obtained from cBioPortal of 5991 breast cancer patients. For ne...

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Literature Corpus work: 82ed226f-ddf8-59bc-8e71-f0f9a46bd051
DOI: 10.1101/2020.02.11.943258

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