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Article

Proactive and reactive roles of TGF-β in cancer

10 Aug 2023

Abstract excerpt

Cancer cells adapt to varying stress conditions to survive through plasticity. Stem cells exhibit a high degree of plasticity, allowing them to generate more stem cells or differentiate them into specialized cell types to contribute to tissue development, growth, and repair. Cancer cells can also exhibit plasticity and acquire properties that enhance their survival. TGF-β is an unrivaled growth factor exploited...

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Identifiers

PMID: 37572731
DOI: 10.1016/j.semcancer.2023.08.002

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