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Article

Purifying selection against spurious splicing signals contributes to the base composition evolution of the polypyrimidine tract.

Journal of evolutionary biology - 1 Sept 2023

Yıldırım Burçin, Vogl Claus

Abstract excerpt

Among eukaryotes, the major spliceosomal pathway is highly conserved. While long introns may contain additional regulatory sequences, the ones in short introns seem to be nearly exclusively related to splicing. Although these regulatory sequences involved in splicing are well-characterized, little is known about their evolution. At the 3' end of introns, the splice signal nearly universally contains the dimer AG,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37564008
DOI: 10.1111/jeb.14205
PMCID: PMC10946897

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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