Article
Mutation pressure, natural selection, and the evolution of base composition in Drosophila.
Genetica - 1 Jan 1998
Akashi H, Kliman R M, Eyre-Walker A
Abstract excerpt
Genome sequencing in a number of taxa has revealed variation in nucleotide composition both among regions of the genome and among functional classes of sites in DNA. Mutational biases, biased gene conversion, and natural selection have been proposed as causes of this variation. Here, we review patterns of base composition in Drosophila DNA. Nucleotide composition in Drosophila melanogaster varys regionally, and...
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