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Article

Biased exon/intron distribution of cryptic and de novo 3' splice sites.

Nucleic acids research - 1 Jan 2005

Královicová Jana, Christensen Mikkel B, Vorechovský Igor

Abstract excerpt

We compiled sequences of previously published aberrant 3' splice sites (3'ss) that were generated by mutations in human disease genes. Cryptic 3'ss, defined here as those resulting from a mutation of the 3'YAG consensus, were more frequent in exons than in introns. They clustered in approximately 20 nt region adjacent to authentic 3'ss, suggesting that their under-representation in introns is due to a depletion...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16141195
DOI: 10.1093/nar/gki811
PMCID: PMC1197134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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