GC-biased segregation of noncoding polymorphisms in Drosophila.

doi:10.1534/genetics.105.046524

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Article

GC-biased segregation of noncoding polymorphisms in Drosophila.

Genetics - 1 Jan 2006

Galtier Nicolas, Bazin Eric, Bierne Nicolas

Abstract excerpt

The study of base composition evolution in Drosophila has been achieved mostly through the analysis of coding sequences. Third codon position GC content, however, is influenced by both neutral forces (e.g., mutation bias) and natural selection for codon usage optimization. In this article, large data sets of noncoding DNA sequence polymorphism in D. melanogaster and D. simulans were gathered from public databases...

Topics

Animals
Base Pairing
Chromosome Mapping
Chromosome Segregation
Drosophila melanogaster
GC Rich Sequence
Mutation
Phylogeny
Polymorphism, Genetic
Selection, Genetic
Untranslated Regions

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Identifiers

PMID: 16157668
DOI: 10.1534/genetics.105.046524
PMCID: PMC1456149

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