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Article

Utilization of Serial Next-Generation Sequencing Among Patients Receiving CPX-351 for Newly Diagnosed Acute Myeloid Leukemia.

Clinical lymphoma, myeloma & leukemia - 1 Oct 2023

Jain Akriti G, Ball Somedeb, Aguirre Luis E, Tobon Katherine A, Chan Onyee, Padron Eric, Kuykendall Andrew, Komrokji Rami, Sallman David, Lancet Jeffrey E, Sweet Kendra

Abstract excerpt

BACKGROUND: The phase III trial that led to the approval of CPX-351 for treating secondary acute myeloid leukemia (sAML) in 2017 did not study the effect of specific mutations on outcomes. METHODS: This retrospective study was done to evaluate the effect of next-generation sequencing (NGS) results at the time of best response and before allogeneic stem cell transplant (alloSCT) in patients treated with CPX-351 as...

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PMID: 37558530
DOI: 10.1016/j.clml.2023.07.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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