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Article

A two-galectin network establishes mesenchymal condensation phenotype in limb development.

Mathematical biosciences - 1 Nov 2023

Glimm T, Kaźmierczak B, Newman S A, Bhat R

Abstract excerpt

Previous work showed that Gal-1A and Gal-8, two proteins belonging to the galactoside-binding galectin family, are the earliest determinants of the patterning of the skeletal elements of embryonic chicken limbs, and further, that their experimentally determined interactions in the embryonic limb bud can be interpreted via a reaction-diffusion-adhesion (2GL: two galectin plus ligands) model. Here, we use an...

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PMID: 37544500
DOI: 10.1016/j.mbs.2023.109054

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