Article
Limb bud and flank mesoderm have distinct "physical phenotypes" that may contribute to limb budding.
Developmental biology - 15 Sept 2008
Damon Brooke J, Mezentseva Nadejda V, Kumaratilake Jaliya S, Forgacs Gabor, Newman Stuart A
Abstract excerpt
Limb bud outgrowth in chicken embryos is initiated during the third day of development by Fibroblast Growth Factor 8 (FGF8) produced by the newly formed apical ectodermal ridge (AER). One of the earliest effects of this induction is a change in the properties of the limb field mesoderm leading to bulging of the limb buds from the body wall. Heintzelman et al. [Heintzelman, K.F., Phillips, H.M., Davis, G.S., 1978....
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