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Article

Embryonic statistical analyses reveal 2 growth phenotypes in mouse models of Down syndrome.

American journal of obstetrics and gynecology - 1 Feb 2024

Adams April D, Lin Jielu, Bianchi Diana W, Bishop Lauren, Sato Taisuke, Baxter Laura L, Hoffmann Victoria, Koehly Laura, Guedj Faycal

Abstract excerpt

BACKGROUND: Down syndrome is associated with several comorbidities, including intellectual disability, growth restriction, and congenital heart defects. The prevalence of Down syndrome-associated comorbidities is highly variable, and intellectual disability, although fully penetrant, ranges from mild to severe. Understanding the basis of this interindividual variability might identify predictive biomarkers of in...

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Identifiers

PMID: 37544351
DOI: 10.1016/j.ajog.2023.07.056
PMCID: PMC10841273

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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