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Article

Novel insights from fetal and placental phenotyping in 3 mouse models of Down syndrome.

American journal of obstetrics and gynecology - 1 Sept 2021

Adams April D, Hoffmann Victoria, Koehly Laura, Guedj Faycal, Bianchi Diana W

Abstract excerpt

BACKGROUND: In human fetuses with Down syndrome, placental pathology, structural anomalies and growth restriction are present. There is currently a significant lack of information regarding the early life span in mouse models of Down syndrome. OBJECTIVE: The objective of this study was to examine embryonic day 18.5 and placental phenotype in the 3 most common mouse models of Down syndrome (Ts65Dn, Dp(16)1/Yey,...

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Source

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Identifiers

PMID: 33766516
DOI: 10.1016/j.ajog.2021.03.019
PMCID: PMC8429205

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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