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Article

Association between polymorphism rs2421943 of the insulin-degrading enzyme and schizophrenia: Preliminary report.

Journal of clinical laboratory analysis - 1 Jul 2023

Ambrozová Laura, Zeman Tomáš, Janout Vladimír, Janoutová Jana, Lochman Jan, Šerý Omar

Abstract excerpt

BACKGROUND: Insulin-degrading enzyme (IDE) is an important gene in studies of the pathophysiology of type 2 diabetes mellitus (T2DM). Recent studies have suggested a possible link between type 2 diabetes mellitus (T2DM) and the pathophysiology of schizophrenia (SZ). At the same time, significant changes in insulin-degrading enzyme (IDE) gene expression have been found in the brains of people with schizophrenia....

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Alzheimer Disease
Diabetes Mellitus, Type 2
Genotype
Insulysin
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37515308
DOI: 10.1002/jcla.24949
PMCID: PMC10492455

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