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Germline whole genome sequencing in adults with multiple primary tumors.

Familial cancer - 1 Oct 2023

Wang Yiming, Ding Qiliang, Prokopec Stephenie, Farncombe Kirsten M, Bruce Jeffrey, Casalino Selina, McCuaig Jeanna, Szybowska Marta, van Engelen Kalene, Lerner-Ellis Jordan, Pugh Trevor J, Kim Raymond H

Abstract excerpt

Multiple primary tumors (MPTs) are a harbinger of hereditary cancer syndromes. Affected individuals often fit genetic testing criteria for a number of hereditary cancer genes and undergo multigene panel testing. Other genomic testing options, such as whole exome (WES) and whole genome sequencing (WGS) are available, but the utility of these genomic approaches as a second-tier test for those with uninformative...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Neoplasms, Multiple Primary

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Identifiers

PMID: 37481477
DOI: 10.1007/s10689-023-00343-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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