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Incidental findings from cancer next generation sequencing panels

19 Jul 2021

Abstract excerpt

Next-generation sequencing (NGS) technologies have facilitated multi-gene panel (MGP) testing to detect germline DNA variants in hereditary cancer patients. This sensitive technique can uncover unexpected, non-germline incidental findings indicative of mosaicism, clonal hematopoiesis (CH), or hematologic malignancies. A retrospective chart review was conducted to identify cases of incidental findings from NGS-MGP...

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PMID: 34282142
DOI: 10.1038/s41525-021-00224-6

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