Article
Thyroid Function in Causal Relation to MRI Markers of Cerebral Small Vessel Disease: A Mendelian Randomization Analysis.
The Journal of clinical endocrinology and metabolism - 18 Aug 2023
Tian Yu, Yao Dongxiao, Jin Aoming, Wang Mengxing, Pan Yuesong, Wang Yongjun, Wang Yilong
Abstract excerpt
CONTEXT: Observational studies have provided insufficient information on the association between thyroid function and the risk of cerebral small vessel disease (CSVD); moreover, the causality of this link is still unclear. OBJECTIVE: This study aims to investigate whether genetically predicted variation within thyroid function is causally associated with the risk of CSVD using 2-sample Mendelian randomization...
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