Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Uncommon variants detected via hereditary cancer panel and suggestions for genetic counseling.

Mutation research - 1 Jan 2000

Özdemir Zeynep, Çevik Ezgi, Öksüzoğlu Ömür Berna Çakmak, Doğan Mutlu, Ateş Öztürk, Esin Ece, Bilgetekin İrem, Demirci Umut, Köseoğlu Çağlar, Topal Alper, Karadurmuş Nuri, Erdem Haktan Bağış, Bahsi Taha

Abstract excerpt

OBJECTIVE: Hereditary cancer syndromes constitute 5-10% of all cancers. The development of next-generation sequencing technologies has made it possible to examine many hereditary cancer syndrome-causing genes in a single panel. This study's goal was to describe the prevalence and the variant spectrum using NGS in individuals who were thought to have a hereditary predisposition for cancer. MATERIAL AND METHOD:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to BRCA1 Protein
Share to BRCA2 Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Genetic Counseling

Share to Genetic Predisposition to Disease

Share to Germ-Line Mutation

Source

Identifiers

PMID: 37453313
DOI: 10.1016/j.mrfmmm.2023.111831

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Uncommon variants detected via hereditary cancer panel and suggestions for genetic counseling.PMID 37453313Read ↗

The Clinical and Genetic Landscape of Hereditary Cancer: Experience from a Single Clinical Diagnostic Laboratory.Semantic proximity Read ↗

Detection of Germline Mutations in Breast Cancer Patients with Clinical Features of Hereditary Cancer Syndrome Using a Multi-Gene Panel Test.Semantic proximity Read ↗

Opportunistic genetic screening increases the diagnostic yield and is medically valuable for care of patients and their relatives with hereditary cancer.Semantic proximity Read ↗

Detection of Germline Mutations in a Cohort of 250 Relatives of Mutation Carriers in Multigene Panel: Impact of Pathogenic Variants in Other Genes beyond <em>BRCA1/2</em>Semantic proximity Read ↗

Analysis of hereditary cancer syndromes by using a panel of genes: novel and multiple pathogenic mutationsSemantic proximity Read ↗

Comprehensive analysis of germline mutations in northern Brazil: a panel of 16 genes for hereditary cancer-predisposing syndrome investigation.Semantic proximity Read ↗

Concurrent pathogenic variations in patients with hereditary cancer syndromes.Semantic proximity Read ↗

[Retrospective NGS Study in High-risk Hereditary Cancer Patients at Masaryk Memorial Cancer Institute].Semantic proximity Read ↗

Multigene panel analysis identified germline mutations of DNA repair genes in breast and ovarian cancerSemantic proximity Read ↗

Development and Validation of a 34-Gene Inherited Cancer Predisposition Panel Using Next-Generation Sequencing.Semantic proximity Read ↗

Whole genome profiling of 400 patients at risk for hereditary cancer in a Brazilian cohortSemantic proximity Read ↗

Characterization of the molecular and clinical features of Multilocus Inherited Neoplasia Allelic Syndrome (MINAS) cases in the Turkish population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.