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Article

Concurrent pathogenic variations in patients with hereditary cancer syndromes.

European journal of medical genetics - 1 Dec 2021

Agaoglu Nihat Bugra, Doganay Levent

Abstract excerpt

Cancer is a multifactorial disorder; however, 5-10% of all cancers show hereditary background. In recent years many targeted next generation sequencing panels comprising cancer predisposition genes have been developed and used for diagnostic purposes in patients with increased cancer risk. Screening multiple genes at a time allows multiple variants in different genes to be detected as well. This study aims to...

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Identifiers

PMID: 34637943
DOI: 10.1016/j.ejmg.2021.104366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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