Article

Whole genome profiling of 400 patients at risk for hereditary cancer in a Brazilian cohort

2025-08-22

Abstract excerpt

<title>Abstract</title> <p>Hereditary cancer syndromes, caused by inherited genetic alterations, account for 5–10% of all cancers, posing substantial diagnostic and management challenges. Despite advances in next-generation sequencing technologies, access to genetic testing remains limited, particularly in low- and middle-income countries (LMICs), such as Brazil. Genetic heterogeneity and complex etiopathogenic p...

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Literature Corpus work: 02ed4467-b15e-5619-bbbd-742cfca474f5
DOI: 10.21203/rs.3.rs-7104192/v1

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