The Clinical and Genetic Landscape of Hereditary Cancer: Experience from a Single Clinical Diagnostic Laboratory.

doi:10.21873/cgp.20463

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The Clinical and Genetic Landscape of Hereditary Cancer: Experience from a Single Clinical Diagnostic Laboratory.

Cancer genomics & proteomics - 1 Jan 2000

Tsoulos Nikolaos, Agiannitopoulos Konstantinos, Potska Kevisa, Katseli Anastasia, Ntogka Christina, Pepe Georgia, Bouzarelou Dimitra, Papathanasiou Athanasios, Grigoriadis Dimitrios, Tsaousis Georgios N, Gogas Helen, Troupis Theodore, Papazisis Konstantinos, Natsiopoulos Ioannis, Venizelos Vassileios, Amarantidis Kyriakos, Giassas Stylianos, Papadimitriou Christos, Fountzilas Elena, Stathoulopoulou Maroulio, Koumarianou Anna, Xepapadakis Grigorios, Blidaru Alexandru, Zob Daniela, Voinea Oana, Özdoğan Mustafa, Ergören Mahmut Çerkez, Hegmane Alinta, Papadopoulou Eirini, Nasioulas George, Markopoulos Christos

Abstract excerpt

BACKGROUND/AIM: The application of next-generation sequencing (NGS) technology in the genetic investigation of hereditary cancer is important for clinical surveillance, therapeutic approach, and reducing the risk of developing new malignancies. The aim of the study was to explore genetic predisposition in individuals referred for hereditary cancer. MATERIALS AND METHODS: A total of 8,261 individuals were referred...

Topics

Humans
Female
Male
Adult
Middle Aged
Genetic Predisposition to Disease
Genetic Testing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Aged

High-Throughput Nucleotide Sequencing

Young Adult

Neoplasms

Laboratories, Clinical

Adolescent

Biomarkers, Tumor

Neoplastic Syndromes, Hereditary

Aged, 80 and over

Source

Open in PubMed Open full text

Identifiers

PMID: 39191493
DOI: 10.21873/cgp.20463
PMCID: PMC11363926

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