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Article

[Retrospective NGS Study in High-risk Hereditary Cancer Patients at Masaryk Memorial Cancer Institute].

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti - 1 Jan 2016

Macháčková E, Hazova J, Sťahlová Hrabincová E, Vašíčková P, Navrátilová M, Svoboda M, Foretová L

Abstract excerpt

BACKGROUND: Currently, more than 200 hereditary cancer syndromes have been described, yet, in most countries genetic testing is restricted to a narrow spectrum of genes within a limited group of people tested. METHODS: For this retrospective study we used the TruSight cancer panel (Illumina)--NGS panel targeting 94 cancer predisposition genes in order to analyze 50 high-risk cancer patients with significant...

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Source

Identifiers

PMID: 26691941
DOI: 10.14735/amko2016s35

Genes

ATM
ERCC2
APC
BAP1
BRCA1
BRCA2
BRIP1
CDH1
CHEK2
ERCC3
ERCC4
FANCA
FANCC
FANCI
MEN1
MLH1
MSH2
MSH6
MUTYH
PALB2
PMS2
RECQL4
RET
SBDS
SDHB
STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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