Article
Characterization of the molecular and clinical features of Multilocus Inherited Neoplasia Allelic Syndrome (MINAS) cases in the Turkish population.
Familial cancer - 8 Jun 2026
Akcan Mehmet Berkay, Duru Ali, Erdoğan Kadri Murat, Özer Kaya Özge, Keşan Selcan, Kırbıyık Özgür, Türk Tuba Sözen, Altunbaş Yalabık Feyza, Kutbay Yaşar Bekir, Anlaş Özlem, Saka Güvenç Merve, Koç Altuğ, Ünal Olçun Ümit, Özyılmaz Berk, Özdemir Taha Reşid
Abstract excerpt
Multilocus Inherited Neoplasia Allelic Syndrome (MINAS) is a rare genetic syndrome characterized by the presence of multiple pathogenic/likely pathogenic(P/LP) variants in different cancer predisposition genes within the same individual. Patients with MINAS may face early age at onset and multiple primary malignancies. In our study, we aimed to characterize the prevalence and clinical landscape of MINAS in a...
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