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Article

Cerebrospinal fluid as a liquid biopsy for molecular characterization of brain metastasis in patients with non-small cell lung cancer.

Lung cancer (Amsterdam, Netherlands) - 1 Aug 2023

Tsakonas Georgios, Tadigotla Vasisht, Chakrabortty Sudipto K, Stragliotto Giuseppe, Chan Dalin, Lewensohn Rolf, Yu Wei, Skog Johan K, Hydbring Per, Ekman Simon

Abstract excerpt

OBJECTIVES: Non-small cell lung cancer (NSCLC) with brain metastases (BM) is a challenging clinical issue with poor prognosis. No data exist regarding extensive genetic analysis of cerebrospinal fluid (CSF) and its correlation to associated tumor compartments. MATERIALS AND METHODS: We designed a study across multiple NSCLC patients with matched material from four compartments; primary tumor, BM, plasma and CSF....

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Identifiers

PMID: 37423059
DOI: 10.1016/j.lungcan.2023.107292

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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