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Article

Cerebrospinal fluid circulating tumor DNA depicts profiling of brain metastasis in NSCLC.

Molecular oncology - 1 May 2023

Wu Jun, Liu Zhiqiang, Huang Tianxiang, Wang Ying, Song Meng Meng, Song Tao, Long Gretchen, Zhang Xiaobing, Li Xi, Zhang Longbo

Abstract excerpt

Brain metastasis (BM) genetically diverges from the primary tumor in non-small-cell lung cancer (NSCLC). Hence, accurately capturing clinically relevant alterations is pivotal for the delivery of targeted therapies. Circulating tumor DNA (ctDNA) sequencing has emerged as a promising liquid biopsy in the biomarker-based clinical management of recurrent and extracranial metastatic NSCLC. However, the absence of...

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Identifiers

PMID: 36495130
DOI: 10.1002/1878-0261.13357
PMCID: PMC10158766

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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