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Pulmonary Langerhans cell histiocytosis – an update on pathogenesis and treatment

6 Jul 2023

Abstract excerpt

PURPOSE OF REVIEW: Pulmonary Langerhans cell histiocytosis (PLCH) is a rare diffuse cystic lung disease that affects young to middle-aged smoking adults of both genders. The identification of molecular alterations in the canonical mitogen-activated protein kinase (MAPK) signalling pathway in most specific lesions has demonstrated the clonal/neoplastic nature of PLCH. We will summarize the progress made in the...

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PMID: 37410483
DOI: 10.1097/mcp.0000000000000988

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