Article
International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults.
Blood - 28 Apr 2022
Goyal Gaurav, Tazi Abdellatif, Go Ronald S, Rech Karen L, Picarsic Jennifer L, Vassallo Robert, Young Jason R, Cox Christian W, Van Laar Jan, Hermiston Michelle L, Cao Xin-Xin, Makras Polyzois, Kaltsas Gregory, Haroche Julien, Collin Matthew, McClain Kenneth L, Diamond Eli L, Girschikofsky Michael
Abstract excerpt
Langerhans cell histiocytosis (LCH) can affect children and adults with a wide variety of clinical manifestations, including unifocal, single-system multifocal, single-system pulmonary (smoking-associated), or multisystem disease. The existing paradigms in the management of LCH in adults are mostly derived from the pediatric literature. Over the last decade, the discovery of clonality and MAPK-ERK pathway...
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