Article
Clinical implications of oncogenic mutations in pulmonary Langerhans cell histiocytosis.
Current opinion in pulmonary medicine - 1 May 2018
Brown Noah A, Elenitoba-Johnson Kojo S J
Abstract excerpt
PURPOSE OF REVIEW: Langerhans cell histiocytosis (LCH) is a neoplasm of dendritic cells with a wide clinical spectrum. Localized pulmonary LCH occurs in young adults with a history of smoking and can either resolve spontaneously or lead to progressive decline in pulmonary function. Young children can also present with localized disease - frequently bone or skin - or with multifocal or multisystem disease....
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