Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Current understanding and management of pulmonary Langerhans cell histiocytosis.

Thorax - 1 Oct 2017

Vassallo Robert, Harari Sergio, Tazi Abdellatif

Abstract excerpt

Pulmonary Langerhans cell histiocytosis (PLCH) is a diffuse lung disease that usually affects young adult smokers. PLCH affects different lung compartments; bronchiolar, interstitial and pulmonary vascular dysfunction may coexist to varying extents, resulting in diverse phenotypes. Analyses of PLCH tissues have identified activating mutations of specific mitogen-activated protein kinases (BRAFV600E and others)....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Progression
Share to BRAF gene
Share to Histiocytosis, Langerhans-Cell

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lung Diseases

Share to Phenotype

Share to Smoking

Source

Identifiers

PMID: 28689173
DOI: 10.1136/thoraxjnl-2017-210125

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Current understanding and management of pulmonary Langerhans cell histiocytosis.PMID 28689173Read ↗

Pulmonary Langerhans cell histiocytosis – an update on pathogenesis and treatmentSemantic proximity Read ↗

Pulmonary Langerhans Cell Histiocytosis.Semantic proximity Read ↗

Pulmonary Langerhans Cell Histiocytosis: An Update From the Pathologists' Perspective.Semantic proximity Read ↗

Pulmonary langerhans cell histiocytosisSemantic proximity Read ↗

International expert consensus recommendations for the diagnosis and treatment of Langerhans cell histiocytosis in adults.Semantic proximity Read ↗

How I manage pulmonary Langerhans cell histiocytosis.Semantic proximity Read ↗

New insights in lymphangioleiomyomatosis and pulmonary Langerhans cell histiocytosis.Semantic proximity Read ↗

Primary pulmonary Langerhans cell histiocytosis: comprehensive clinicopathologic and molecular genetic analysis of 13 cases.Semantic proximity Read ↗

Clinical implications of oncogenic mutations in pulmonary Langerhans cell histiocytosis.Semantic proximity Read ↗

Langerhans cell histiocytosis. Advances in pathogenesis and clinical practice.Semantic proximity Read ↗

Clinical features and treatment of Langerhans cell histiocytosis.Semantic proximity Read ↗

Langerhans Cell-Rich Fibroinflammatory Pulmonary Lesion Presenting as a Pulmonary Mass: A Case ReportSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.