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Article

An efficient evaluation system for factors affecting the genome editing efficiency in mouse.

Experimental animals - 9 Nov 2023

Sakai Yusuke, Okabe Yuri, Itai Gen, Shiozawa Seiji

Abstract excerpt

Genome editing technology is widely used in the field of laboratory animal science for the production of genetic disease models and the analysis of gene function. One of the major technical problems in genome editing is the low efficiency of precise knock-in by homologous recombination compared to simple knockout via non-homologous end joining. Many studies have focused on this issue, and various solutions have...

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Identifiers

PMID: 37407493
DOI: 10.1538/expanim.23-0045
PMCID: PMC10658088

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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