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Article

Evaluation of microRNA variant maturation prior to genome edition.

Biochimie - 1 Feb 2024

Busseau Isabelle, Mockly Sophie, Houbron Élisabeth, Somaï Hedi, Seitz Hervé

Abstract excerpt

Assessment of the functionality of individual microRNA/target sites is a crucial issue. Genome editing techniques should theoretically permit a fine functional exploration of such interactions, allowing the mutation of microRNAs or individual binding sites in a complete in vivo setting, therefore abrogating or restoring individual interactions on demand. A major limitation to this experimental strategy is the...

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PMID: 37385398
DOI: 10.1016/j.biochi.2023.06.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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