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Article

Systematic study of Drosophila microRNA functions using a collection of targeted knockout mutations.

Developmental cell - 22 Dec 2014

Chen Ya-Wen, Song Shilin, Weng Ruifen, Verma Pushpa, Kugler Jan-Michael, Buescher Marita, Rouam Sigrid, Cohen Stephen M

Abstract excerpt

MicroRNAs are abundant in animal genomes, yet little is known about their functions in vivo. Here, we report the production of 80 new Drosophila miRNA mutants by targeted homologous recombination. These mutants remove 104 miRNAs. Together with 15 previously reported mutants, this collection inclu...

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PMID: 25535920
DOI: 10.1016/j.devcel.2014.11.029

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25535920-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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